Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | CLPP | Q16740 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856229 | 0.98 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6853905 | 0.94 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6855333 | 0.92 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6853858 | 0.92 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6854118 | 0.91 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6856899 | 0.89 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6855322 | 0.88 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6996136 | 0.88 | MAPT (0.51) | L3MBTL1ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6850175 | 0.88 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL6855573 | 0.88 | MAPT (0.49) | L3MBTL1ALDH1A1HTTKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002543199-A | — | — | 2002-12-17 | — | — | JP | claimed |
| EP-1177195-A1 | 1-AMINO TRIAZOLO 4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER-LAMBERT COMPANY (US) | 2002-02-06 | — | — | EP | claimed |
| WO-2000066584-B1 | 1-AMINO TRIAZOLO¢4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER LAMBERT CO (US) | 2001-02-15 | — | — | WO | claimed |
| WO-2000066584-A1 | 1-AMINO TRIAZOLO¢4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER-LAMBERT COMPANY (US) | 2000-11-09 | — | — | WO | claimed |