Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 10/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037256 | 0.96 | CCR5 (0.66) | CCR5OPRM1ACHE | |
| SCHEMBL7462810 | 0.93 | CCR5 (0.63) | CCR5OPRM1ACHE | |
| SCHEMBL7463509 | 0.93 | CCR5 (0.60) | CCR5OPRM1ACHE | |
| SCHEMBL7462545 | 0.93 | CCR5 (0.59) | CCR5OPRM1ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL7466859 | 0.92 | CCR5 (0.60) | CCR5OPRM1ACHE | |
| SCHEMBL7459649 | 0.92 | CCR5 (0.58) | CCR5SLC6A2SLC6A4 | |
| SCHEMBL7459658 | 0.91 | OPRM1 (0.63) | CCR5OPRM1ALDH1A1ACHE | |
| SCHEMBL7463909 | 0.91 | CCR5 (0.58) | CCR5OPRM1SLC6A2SLC6A4ACHE | |
| SCHEMBL3040135 | 0.91 | CCR5 (0.61) | CCR5OPRM1ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL7458584 | 0.89 | CCR5 (0.65) | CCR5OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180513-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-20 | — | — | EP | disclosed |