Thioglycolic Acid

Thioglycolic Acid

SCHEMBL746614

CCCC[Sn]CCCC.O=C(O)CS

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.42
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.41
PPARD Q03181 8/20 0.41
GPR84 Q9NQS5 7/20 0.41
PPARG P37231 7/20 0.41
PPARA Q07869 7/20 0.41
HDAC11 Q96DB2 5/20 0.41
TSHR P16473 4/20 0.41
PTPN1 P18031 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TLR2 O60603 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FABP4 P15090 2/20 0.41
HSD17B10 Q99714 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
MEN1 O00255 1/20 0.41
ESR1 P03372 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL8425115 1.00 AKR1B1 (0.42) AKR1B1KMT2AMAPTPPARDGPR84
Thioglycolic Acid SCHEMBL11366524 0.91 KMT2A (0.48) AKR1B1KMT2AMAPTPPARDGPR84
Propionic Acid SCHEMBL8384766 0.85 FFAR3 (0.53) AKR1B1KMT2AMAPTPPARDGPR84
Fumaric Acid SCHEMBL11672390 0.85 HCAR2 (0.45) KMT2AMAPTPPARDGPR84PPARG
Bicarbonate SCHEMBL27704868 0.85 AKR1B1 (0.43) AKR1B1KMT2APPARDGPR84PPARG
Mercaptopropionic Acid SCHEMBL361822 0.85 AKR1B1 (0.48) AKR1B1KMT2AMAPTPPARDGPR84
Mercaptopropionic Acid SCHEMBL3643726 0.85 AKR1B1 (0.48) AKR1B1KMT2AMAPTPPARDGPR84
Thioglycolic Acid SCHEMBL27506823 0.84 PPARD (0.41) KMT2AMAPTPPARDGPR84PPARG
Malonic Acid SCHEMBL4616186 0.83 LDHA (0.45) AKR1B1KMT2AMAPTPPARDGPR84
Succinic Acid SCHEMBL3977808 0.83 AKR1B1 (0.56) AKR1B1KMT2AMAPTPPARDGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4532074-A Including thermoplastic vinyl chloride polymer, finely divided carbon black, organometallic stabilizer, plasticizer, isopropyl tri/dioctylpyrophosphato/titanate RCA CORPORATION (US) 1985-07-30 US claimed
JP-63268756-A None JP disclosed
EP-2907844-B1 RESIN COMPOSITION FOR PRINTING FILM AND PRINTING FILM ADEKA CORP (JP) 2017-09-20 EP disclosed
EP-3030610-B1 HEAT STABILIZER FOR HALOGEN-CONTAINING POLYMERS GALATA CHEMICALS LLC (US) 2017-05-17 EP disclosed
US-9587088-B2 Heat stabilizer for halogen-containing polymers GALATA CHEMICALS LLC (US) 2017-03-07 US disclosed
EP-2256161-B1 FLAME-RETARDANT CHLORINE-CONTAINING RESIN COMPOSITION ADEKA CORP (JP) 2017-01-11 EP disclosed
US-20160194478-A1 HEAT STABILIZER FOR HALOGEN-CONTAINING POLYMERS CITIZENS BANK, N.A. 2016-07-07 US disclosed
EP-3030610-A1 HEAT STABILIZER FOR HALOGEN-CONTAINING POLYMERS Galata Chemicals LLC (US) 2016-06-15 EP disclosed
US-20150232626-A1 RESIN COMPOSITION FOR PRINTING FILM AND PRINTING FILM ADEKA CORPORATION (JP) 2015-08-20 US disclosed
EP-2907844-A1 RESIN COMPOSITION FOR PRINTING FILM AND PRINTING FILM Adeka Corporation (JP) 2015-08-19 EP disclosed
EP-0407139-B1 Stabilizer composition for use in halogen-containing resins KYOWA CHEM IND CO LTD (JP) 1995-01-18 EP disclosed
US-5356981-A An inorganic copper compound adsorbed into hydrotalcite; polyvinyl chloride ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1994-10-18 US disclosed
EP-0483400-A1 Stabilized chlorinated resin composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1992-05-06 EP disclosed
US-5106898-A Dehydrated hydrotalcite and lubricant KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) 1992-04-21 US disclosed
EP-0407139-A1 Stabilizer composition for use in halogen-containing resins KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) 1991-01-09 EP disclosed
EP-0356954-A2 A plasticized polyvinyl alcohol release layer for a flexographic printing plate E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-07 EP disclosed
US-4371656-A Metal substituted zeolites as stabilizers for halogen-containing resins NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) 1983-02-01 US disclosed
US-4146518-A ORGANOTIN COMPOUNDS ARGUS CHEMICAL CORPORATION (US) 1979-03-27 US disclosed
US-4000216-A CROSSLINKED ADDITION POLYMERS ROHM AND HAAS COMPANY (US) 1976-12-28 US disclosed
US-3969469-A IMPACT RESISTANT TENNECO CHEMICALS, INC. (US) 1976-07-13 US disclosed