Thioglycolic Acid

Thioglycolic Acid

SCHEMBL8425115

CCCC[Sn]CCCC.O=C(O)CS.O=C(O)CS

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.42
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.41
PPARD Q03181 8/20 0.41
GPR84 Q9NQS5 7/20 0.41
PPARG P37231 7/20 0.41
PPARA Q07869 7/20 0.41
HDAC11 Q96DB2 5/20 0.41
TSHR P16473 4/20 0.41
PTPN1 P18031 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TLR2 O60603 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FABP4 P15090 2/20 0.41
HSD17B10 Q99714 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
MEN1 O00255 1/20 0.41
ESR1 P03372 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL746614 1.00 AKR1B1 (0.42) AKR1B1KMT2AMAPTPPARDGPR84
Thioglycolic Acid SCHEMBL11366524 0.91 KMT2A (0.48) AKR1B1KMT2AMAPTPPARDGPR84
Propionic Acid SCHEMBL8384766 0.85 FFAR3 (0.53) AKR1B1KMT2AMAPTPPARDGPR84
Fumaric Acid SCHEMBL11672390 0.85 HCAR2 (0.45) KMT2AMAPTPPARDGPR84PPARG
Bicarbonate SCHEMBL27704868 0.85 AKR1B1 (0.43) AKR1B1KMT2APPARDGPR84PPARG
Mercaptopropionic Acid SCHEMBL361822 0.85 AKR1B1 (0.48) AKR1B1KMT2AMAPTPPARDGPR84
Mercaptopropionic Acid SCHEMBL3643726 0.85 AKR1B1 (0.48) AKR1B1KMT2AMAPTPPARDGPR84
Thioglycolic Acid SCHEMBL27506823 0.84 PPARD (0.41) KMT2AMAPTPPARDGPR84PPARG
Malonic Acid SCHEMBL4616186 0.83 LDHA (0.45) AKR1B1KMT2AMAPTPPARDGPR84
Succinic Acid SCHEMBL3977808 0.83 AKR1B1 (0.56) AKR1B1KMT2AMAPTPPARDGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5688890-A Thermoplastic polyurethane composition KURARAY CO., LTD. (JP) 1997-11-18 US claimed
EP-3960450-A1 THERMOPLASTIC POLYURETHANE RESIN ELASTOMER Mitsubishi Chemical Corporation (JP) 2022-03-02 EP disclosed
EP-2881412-B1 THERMOPLASTIC POLYURETHANE AND A COMPOSITION THEREOF KURARAY CO (JP) 2019-06-26 EP disclosed
US-9593200-B2 Thermoplastic polyurethane and a composition thereof KURARAY CO., LTD. (JP) 2017-03-14 US disclosed
EP-2492296-B1 Resin composition for laser engraving, relief printing plate precursor and process for producing the same, and relief printing plate FUJIFILM CORP (JP) 2015-12-16 EP disclosed
US-20150210799-A1 THERMOPLASTIC POLYURETHANE AND A COMPOSITION THEREOF KURARAY CO., LTD. (JP) 2015-07-30 US disclosed
EP-2881412-A1 THERMOPLASTIC POLYURETHANE AND A COMPOSITION THEREOF Kuraray Co., Ltd. (JP) 2015-06-10 EP disclosed
EP-2492296-A2 Resin composition for laser engraving, relief printing plate precursor and process for producing the same, and relief printing plate Fujifilm Corporation (JP) 2012-08-29 EP disclosed
US-20120211925-A1 METHOD FOR PRODUCING RELIEF PRINTING PLATE PRECURSOR AND METHOD FOR MAKING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-08-23 US disclosed
EP-0651017-B1 THERMOPLASTIC POLYURETHANE COMPOSITION KURARAY CO (JP) 1999-10-27 EP disclosed
US-5688890-A Thermoplastic polyurethane composition KURARAY CO., LTD. (JP) 1997-11-18 US disclosed
EP-0651017-A1 THERMOPLASTIC POLYURETHANE COMPOSITION KURARAY CO., LTD. (JP) 1995-05-03 EP disclosed
US-4280940-A TRANSPARENT COMPOSITIONS OF GOOD VISCOSITY AND RESISTANCE TO LIGHT AND WEATHER HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-28 US disclosed