Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL27411567 | 0.89 | — | — | |
| SCHEMBL28081536 | 0.86 | — | — | |
| SCHEMBL9561094 | 0.76 | — | — | |
| Lindane SCHEMBL4515334 | 0.72 | — | — | |
| Lindane SCHEMBL1016220 | 0.69 | LMNA (0.39) | — | |
| Phosphine SCHEMBL28937317 | 0.68 | — | — | |
| Lindane SCHEMBL2579810 | 0.67 | LMNA (0.36) | — | |
| Lindane SCHEMBL333037 | 0.67 | LMNA (0.36) | — | |
| Lindane SCHEMBL4354321 | 0.67 | LMNA (0.36) | — | |
| SCHEMBL16597718 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242404-A1 | PHENOXYPROPANOLAMINES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044227-A1 | PHENOXYPROPANOLAMINES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2001-06-21 | — | — | WO | disclosed |