Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.81 |
| ▸ | FEN1 | P39748 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466207 | 0.92 | CMA1 (0.85) | CMA1FEN1CA9CA12CA1 | |
| SCHEMBL7461813 | 0.90 | CMA1 (0.68) | CMA1FEN1CA9CA12CA1 | |
| SCHEMBL7463672 | 0.89 | CMA1 (1.00) | CMA1FEN1CA9CA12CA1 | |
| SCHEMBL7472683 | 0.85 | CMA1 (0.81) | CMA1FEN1CA9CA12CA1 | |
| SCHEMBL3775614 | 0.82 | CMA1 (0.85) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL7465666 | 0.82 | CMA1 (0.85) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL3788201 | 0.82 | CMA1 (0.85) | CMA1FEN1CA9CA12CA1 | |
| SCHEMBL7464965 | 0.82 | CMA1 (0.85) | CMA1FEN1CA9CA12CA1 | |
| SCHEMBL7467623 | 0.81 | CMA1 (0.75) | CMA1CA9CA12CA1CA2 | |
| SCHEMBL7460750 | 0.81 | CMA1 (0.75) | CMA1CA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |