Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.48 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466421 | 1.00 | MEN1 (0.55) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18983598 | 0.79 | SCN9A (0.53) | MEN1KMT2ASMN1; SMN2MAPTPSMB8 | |
| SCHEMBL18983593 | 0.79 | SCN9A (0.53) | MEN1KMT2ASMN1; SMN2MAPTPSMB8 | |
| SCHEMBL18983568 | 0.75 | SMN1; SMN2 (0.56) | MEN1KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL4526386 | 0.75 | FPR2 (0.67) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14106361 | 0.75 | MEN1 (0.61) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14105824 | 0.75 | MEN1 (0.61) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7470299 | 0.74 | MGLL (0.62) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18114095 | 0.74 | MEN1 (0.74) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10260922 | 0.74 | SMN1; SMN2 (0.65) | SMN1; SMN2GAAGPR142PSMB8PSMB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6458959-B1 | VIRICIDES AND ENZYME INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-10-01 | — | — | US | disclosed |
| US-6348477-B1 | SUBSTITUTED PHENYL THIAZOLE DERIVATIVES AS VIRICIDES | BOEHRINGER INGELHEIM(CANADA) LTD. (CA) | 2002-02-19 | — | — | US | disclosed |
| US-6288091-B1 | COMPOUNDS SUCH AS 2,2,2-TRICHLOROETHYL N-(4-(2-AMINO-4-THIAZOLYL)-PHENYL)CARBAMATE THAT INHIBIT THE HERPES HELCASE-PRIMASE ENZYME COMPLEX | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-11 | — | — | US | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |