SCHEMBL7466570

SCHEMBL7466570

Nc1cc(Cl)c(N(CCO)CCO)c(-c2ccoc2)c1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.41
ADORA2B P29275 1/20 0.31
ADORA1 P30542 1/20 0.31
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7558041 0.85 CSNK2A1 (0.33) CSNK2A1
SCHEMBL7456164 0.77 CSNK2A1 (0.35) CSNK2A1ADORA2BADORA1
SCHEMBL7459254 0.76 CSNK2A1 (0.41) CSNK2A1ADORA2BADORA1GSK3B
SCHEMBL7460696 0.76 CSNK2A1 (0.41) CSNK2A1ADORA2BADORA1GSK3B
SCHEMBL7812324 0.76 ADORA2A (0.39) ADORA2BADORA1
SCHEMBL7458650 0.76 CSNK2A1 (0.41) CSNK2A1ADORA2BADORA1GSK3B
SCHEMBL7459423 0.76 CYP2A6 (0.36) ADORA1
SCHEMBL7461140 0.76 STK4 (0.30)
SCHEMBL7466921 0.74 PIK3CD (0.32)
SCHEMBL7466976 0.74 CSNK2A1 (0.47) CSNK2A1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963982-B1 New diaminobenzene derivatives and these componends containing colouring agents WELLA AG (DE) 2002-03-13 EP disclosed
US-6132475-A FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS WELLA AKTIENGESELLSCHAFT (DE) 2000-10-17 US disclosed
EP-1017678-A1 1,5-DIPHENYLPYRAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-12 EP disclosed
EP-0963982-A2 New diaminobenzene derivatives and these componends containing colouring agents Wella Aktiengesellschaft (DE) 1999-12-15 EP disclosed
WO-1999015505-A1 1,5-DIPHENYLPYRAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-04-01 WO disclosed