Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457314 | 0.79 | CSNK2A1 (0.37) | CSNK2A1CYP3A4ALDH1A1IMPDH2TSHR | |
| SCHEMBL7466570 | 0.74 | CSNK2A1 (0.41) | CSNK2A1GSK3B | |
| SCHEMBL7459254 | 0.74 | CSNK2A1 (0.41) | CSNK2A1MEN1KMT2AGSK3B | |
| SCHEMBL5174258 | 0.73 | ALDH1A1 (0.52) | CSNK2A1CYP3A4ALDH1A1TSHRTHRB | |
| SCHEMBL7460202 | 0.73 | CSNK2A1 (0.49) | CSNK2A1CYP3A4ALDH1A1IMPDH2TSHR | |
| SCHEMBL7453950 | 0.72 | CSNK2A1 (0.40) | CSNK2A1CYP3A4ALDH1A1IMPDH2TSHR | |
| Hydrochloric Acid SCHEMBL7453311 | 0.70 | CSNK2A1 (0.42) | CSNK2A1CYP3A4ALDH1A1IMPDH2THRB | |
| SCHEMBL1018770 | 0.69 | MAP4K4 (0.42) | CSNK2A1CYP3A4ALDH1A1IMPDH2RET | |
| SCHEMBL1383424 | 0.69 | PELI1 (0.54) | CSNK2A1CYP3A4ALDH1A1TSHRTHRB | |
| SCHEMBL5795534 | 0.69 | ALDH1A1 (0.43) | CSNK2A1CYP3A4ALDH1A1IMPDH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963982-B1 | New diaminobenzene derivatives and these componends containing colouring agents | WELLA AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-6132475-A | FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | disclosed |
| EP-0963982-A2 | New diaminobenzene derivatives and these componends containing colouring agents | Wella Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | disclosed |