Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3055857 | 0.86 | ALOX12 (0.45) | ABCB1METAP1TRPA1CA1CA2 | |
| SCHEMBL4185639 | 0.85 | METAP1 (0.39) | ABCB1METAP1TRPA1HSD17B10CNR2 | |
| SCHEMBL8220279 | 0.84 | METAP1 (0.43) | ABCB1METAP1TRPA1CA1CA2 | |
| SCHEMBL15676168 | 0.82 | METAP1 (0.40) | ABCB1METAP1TRPA1CA1CA2 | |
| SCHEMBL9593998 | 0.82 | METAP1 (0.42) | ABCB1METAP1TRPA1CNR2 | |
| SCHEMBL7295320 | 0.77 | CA1 (0.44) | ABCB1METAP1CA1CA2CA7 | |
| SCHEMBL7309940 | 0.77 | CA1 (0.44) | ABCB1METAP1CA1CA2CA7 | |
| SCHEMBL9725745 | 0.77 | CA1 (0.44) | ABCB1METAP1CA1CA2CA7 | |
| SCHEMBL9725752 | 0.77 | CA1 (0.44) | ABCB1METAP1CA1CA2CA7 | |
| SCHEMBL7295314 | 0.77 | CA1 (0.44) | ABCB1METAP1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733882-A | Retroviral protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-31 | — | — | US | disclosed |