Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295320 | 1.00 | CA1 (0.44) | CA1CA2CA7ALOX12ALOX15 | |
| SCHEMBL7309940 | 1.00 | CA1 (0.44) | CA1CA2CA7ALOX12ALOX15 | |
| SCHEMBL7295314 | 1.00 | CA1 (0.44) | CA1CA2CA7ALOX12ALOX15 | |
| SCHEMBL9725745 | 1.00 | CA1 (0.44) | CA1CA2CA7ALOX12ALOX15 | |
| SCHEMBL9849779 | 0.91 | GAA (0.47) | AAK1CTSLCTSBCTSSCTSK | |
| SCHEMBL9849789 | 0.91 | GAA (0.47) | AAK1CTSLCTSBCTSSCTSK | |
| SCHEMBL6577311 | 0.88 | CA1 (0.40) | CA1CA2CA7ALOX12ALOX15 | |
| SCHEMBL31341367 | 0.84 | CNR2 (0.39) | CA1CA2CA7ALOX12ALOX15 | |
| SCHEMBL15676168 | 0.84 | METAP1 (0.40) | CA1CA2CA7ALOX12ALOX15 | |
| SCHEMBL9740196 | 0.83 | REN (0.41) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |