Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.68 |
| ▸ | CCR2 | P41597 | 8/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460707 | 0.94 | MCHR1 (0.76) | MCHR1CCR2DRD2SIGMAR1KCNA3 | |
| SCHEMBL7463951 | 0.92 | MCHR1 (0.68) | MCHR1DRD2SIGMAR1PRCPCCR1 | |
| SCHEMBL7464970 | 0.90 | MCHR1 (0.55) | MCHR1CCR2DRD2SIGMAR1KCNA3 | |
| SCHEMBL7461814 | 0.89 | MCHR1 (0.54) | MCHR1DRD2SIGMAR1KCNA3CACNA1G | |
| SCHEMBL7463853 | 0.87 | MCHR1 (0.61) | MCHR1DRD2SIGMAR1KCNA3CACNA1G | |
| SCHEMBL7461074 | 0.84 | MCHR1 (0.54) | MCHR1DRD2SIGMAR1CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7461498 | 0.84 | MCHR1 (0.87) | MCHR1CCR2DRD2CACNA1GTACR1 | |
| SCHEMBL7464781 | 0.81 | MCHR1 (0.73) | MCHR1CCR2DRD2SIGMAR1KCNA3 | |
| SCHEMBL7463098 | 0.81 | MCHR1 (1.00) | MCHR1SIGMAR1KCNA3CCR1CCR3 | |
| Hydrochloric Acid SCHEMBL7463694 | 0.80 | MCHR1 (0.98) | MCHR1SIGMAR1CCR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |