Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | CCR2 | P41597 | 5/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | USP5 | P45974 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | CCR3 | P51677 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470119 | 0.94 | MCHR1 (0.68) | MCHR1SIGMAR1DRD2CCR2KCNA3 | |
| SCHEMBL7459547 | 0.90 | MCHR1 (0.65) | MCHR1DRD2CCR2 | |
| SCHEMBL7460592 | 0.90 | MCHR1 (0.62) | MCHR1SIGMAR1DRD2HTR7CCR3 | |
| SCHEMBL7460278 | 0.87 | MCHR1 (0.71) | MCHR1SIGMAR1KCNA3HTR7CCR3 | |
| SCHEMBL7463521 | 0.87 | MCHR1 (0.66) | MCHR1KCNA3HTR7CCR3CCR1 | |
| SCHEMBL7461314 | 0.87 | MCHR1 (0.61) | MCHR1SIGMAR1DRD2CCR2HTR7 | |
| SCHEMBL7461973 | 0.87 | MCHR1 (0.58) | MCHR1SIGMAR1DRD2CCR3CCR1 | |
| SCHEMBL7464749 | 0.86 | MCHR1 (0.61) | MCHR1DRD2CCR2USP5HTR7 | |
| SCHEMBL7460992 | 0.86 | MCHR1 (0.60) | MCHR1SIGMAR1DRD2CCR2USP5 | |
| SCHEMBL7463548 | 0.86 | MCHR1 (0.60) | MCHR1SIGMAR1DRD2CCR2USP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |