Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463853 | 0.95 | MCHR1 (0.61) | MCHR1SIGMAR1CACNA1GKCNH2KCNA3 | |
| SCHEMBL7461074 | 0.94 | MCHR1 (0.54) | MCHR1SIGMAR1DRD2CCR1CCR3 | |
| SCHEMBL7461814 | 0.92 | MCHR1 (0.54) | MCHR1SIGMAR1CACNA1GKCNH2KCNA3 | |
| SCHEMBL7466658 | 0.90 | MCHR1 (0.68) | MCHR1SIGMAR1CACNA1GCCR2KCNA3 | |
| SCHEMBL7460707 | 0.84 | MCHR1 (0.76) | MCHR1SIGMAR1CCR2KCNA3DRD2 | |
| SCHEMBL7463233 | 0.83 | MCHR1 (0.80) | MCHR1DRD4CCR1CCR3CHRM4 | |
| Hydrochloric Acid SCHEMBL7465677 | 0.82 | MCHR1 (0.79) | MCHR1DRD4CCR1CCR3CHRM4 | |
| SCHEMBL7463951 | 0.82 | MCHR1 (0.68) | MCHR1SIGMAR1DRD2CCR1CCR3 | |
| SCHEMBL7464981 | 0.81 | CACNA1G (0.41) | MCHR1CACNA1GKCNH2CCR2DRD2 | |
| SCHEMBL7465649 | 0.80 | MCHR1 (0.46) | MCHR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |