SCHEMBL7466763

SCHEMBL7466763

O=C(O)c1ccc2scc(O)c2c1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
TSHR P16473 4/20 0.40
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA12 O43570 3/20 0.40
CA7 P43166 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 3/20 0.40
CYP1A2 P05177 1/20 0.39
SELL P14151 1/20 0.37
SELP P16109 1/20 0.37
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
CASP1 P29466 1/20 0.35
HMGB1 P09429 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6182352 0.78 ALDH1A1 (0.41) ALDH1A1TSHRCA1CA2CA12
Hydrochloric Acid SCHEMBL7464629 0.76 ALDH1A1 (0.40) ALDH1A1TSHRCA1CA2CA12
SCHEMBL7476511 0.74 TSHR (0.40) ALDH1A1TSHRKDM4EMEN1KMT2A
SCHEMBL9117761 0.72 ALDH1A1 (0.42) ALDH1A1TSHRCA1CA2CA12
SCHEMBL217628 0.70 TSHR (0.61) ALDH1A1TSHRCA1CA2CA12
SCHEMBL32690872 0.70 TSHR (0.61) ALDH1A1TSHRCA1CA2CA12
SCHEMBL11682380 0.69 ALDH1A1 (0.53) ALDH1A1TSHRCA1CA2CA12
SCHEMBL529328 0.69 SELL (0.54) ALDH1A1TSHRCA1CA2CA12
SCHEMBL3808419 0.68 TSHR (0.41) ALDH1A1TSHRCYP1A2MEN1KMT2A
SCHEMBL6130704 0.68 KDM4E (0.45) ALDH1A1TSHRCA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0636622-B1 Isoxazole derivatives and their use as herbicides AVENTIS AGRICULTURE LTD (GB) 2002-10-23 EP disclosed
EP-1160244-A1 Isoxazole derivatives and their use as herbicides RHONE-POULENC AGRICULTURE LIMITED (GB) 2001-12-05 EP disclosed
US-5489570-A PRE- OR POST-EMERGENCE RHONE-POULENC AGRICULTURE LIMITED (GB) 1996-02-06 US disclosed
WO-1995025099-A1 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES RHONE-POULENC AGRICULTURE LTD. (GB) 1995-09-21 WO disclosed
EP-0636622-A1 Isoxazole derivatives and their use as herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1995-02-01 EP disclosed