Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7462872 | 0.99 | TSHR (0.39) | TSHRHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL7462861 | 0.89 | KMT2A (0.38) | TSHRALDH1A1LMNATDP1KMT2A | |
| SCHEMBL7467904 | 0.86 | CA12 (0.41) | TSHRHSD17B10ALDH1A1LMNATDP1 | |
| SCHEMBL6182352 | 0.84 | ALDH1A1 (0.41) | TSHRALDH1A1HPGDTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL7464629 | 0.83 | ALDH1A1 (0.40) | TSHRALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL7469824 | 0.82 | TSHR (0.42) | TSHRHSD17B10ALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL7464266 | 0.81 | TSHR (0.41) | TSHRHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL7472213 | 0.80 | MAPT (0.35) | TSHRALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7464261 | 0.76 | KMT2A (0.34) | TSHRHSD17B10ALDH1A1TDP1KMT2A | |
| SCHEMBL7475097 | 0.75 | MAPT (0.32) | TSHRALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |