Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.41 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471116 | 0.97 | HTT (0.52) | HTTHTR6NR2F2HRH4TTBK1 | |
| SCHEMBL7469367 | 0.92 | MAPT (0.44) | HTTHTR6KMT2AWDR5MAPT | |
| SCHEMBL7467064 | 0.92 | HTR6 (0.52) | HTTHTR6CNR1CNR2MAPT | |
| SCHEMBL7466302 | 0.89 | HTT (0.45) | HTTHTR6NR2F2KMT2AWDR5 | |
| SCHEMBL7472747 | 0.88 | HTT (0.49) | HTTHTR6NR2F2TTBK1TTBK2 | |
| SCHEMBL7469384 | 0.88 | HTT (0.46) | HTTHTR6KMT2AWDR5MAPT | |
| SCHEMBL7464149 | 0.88 | HTR6 (0.44) | HTTHTR6HRH4KMT2AWDR5 | |
| SCHEMBL7465445 | 0.88 | HTR6 (0.55) | HTTHTR6CNR1CNR2KMT2A | |
| SCHEMBL7466158 | 0.88 | HTR6 (0.55) | HTTHTR6CNR1CNR2MAPT | |
| SCHEMBL7470023 | 0.87 | HTR6 (0.44) | HTTHTR6NR2F2HRH4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |