Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466302 | 0.92 | HTT (0.45) | HTR6CDK1PDE5AHTTKMT2A | |
| SCHEMBL7471116 | 0.91 | HTT (0.52) | HTR6PDE5AHTTKMT2AMEN1 | |
| SCHEMBL7472747 | 0.91 | HTT (0.49) | HTR6CDK1PDE5AHTTKMT2A | |
| SCHEMBL7469384 | 0.91 | HTT (0.46) | HTR6CDK1PDE5AHTTKMT2A | |
| SCHEMBL7466331 | 0.91 | ALDH1A1 (0.48) | HTR6PDE5AHTTKMT2AMEN1 | |
| SCHEMBL7466158 | 0.91 | HTR6 (0.55) | HTR6HTTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7471138 | 0.91 | MAPT (0.45) | HTR6PDE5AKMT2AMAPK1MEN1 | |
| SCHEMBL7473892 | 0.90 | HTR6 (0.45) | HTR6CDK1PDE5AHTTKMT2A | |
| SCHEMBL7469367 | 0.88 | MAPT (0.44) | HTR6CDK1PDE5AHTTKMT2A | |
| SCHEMBL7466801 | 0.88 | HTT (0.48) | HTR6CDK1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |