Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 6/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26420117 | 0.90 | BCAT2 (0.34) | MAPTKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL22519753 | 0.90 | BCAT2 (0.35) | MAPTKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL7893338 | 0.88 | PPOX (0.36) | MAPTKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL9036189 | 0.86 | PPOX (0.34) | MAPTKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL7887261 | 0.86 | PPOX (0.34) | MAPTKDM4ECYP1A2CYP2C19GLA | |
| SCHEMBL7656343 | 0.82 | BCAT2 (0.37) | BCAT2BCAT1 | |
| SCHEMBL9469470 | 0.81 | BCAT2 (0.39) | MAPTKDM4EGAAHSD17B10ALDH1A1 | |
| SCHEMBL24244237 | 0.80 | BCAT2 (0.33) | BCAT2BCAT1 | |
| SCHEMBL22519793 | 0.80 | BCAT2 (0.34) | BCAT2BCAT1 | |
| SCHEMBL22519951 | 0.80 | BCAT2 (0.35) | BCAT2BCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495491-B1 | HERBICIDES AND INSECTICIDES; DEFOLIANTS, DESICCANTS, HAULM KILLERS AND ESPECIALLY WEED KILLERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | disclosed |
| EP-1225171-A1 | Substituted cyanophenyluracils | BAYER AG (DE) | 2002-07-24 | — | — | EP | disclosed |