Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467449 | 1.00 | ATM (0.43) | ATMEPHX2MAPTMEN1KMT2A | |
| SCHEMBL7473206 | 0.92 | ATM (0.45) | ATMEPHX2MEN1KMT2AITGB1 | |
| SCHEMBL7468535 | 0.92 | ATM (0.45) | ATMEPHX2MEN1KMT2AITGB1 | |
| SCHEMBL7467208 | 0.89 | ITGB1 (0.42) | ATMMAPTMEN1KMT2AITGB1 | |
| SCHEMBL7465560 | 0.89 | ITGB1 (0.42) | ATMMAPTMEN1KMT2AITGB1 | |
| SCHEMBL7467182 | 0.88 | DGAT1 (0.45) | MAPTMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL7468077 | 0.88 | DGAT1 (0.45) | MAPTMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL7467434 | 0.87 | ITGB1 (0.50) | ATMEPHX2MAPTMEN1KMT2A | |
| SCHEMBL7467373 | 0.86 | ATM (0.46) | ATMMEN1KMT2AITGB1ITGA4 | |
| SCHEMBL7463616 | 0.83 | ITGB1 (0.45) | ATMMAPTMEN1KMT2AITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |