Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687421 | 0.89 | ITGB1 (0.51) | ITGB1ITGA4POLBSMN1; SMN2ITGB3 | |
| SCHEMBL7467201 | 0.89 | ITGB1 (0.51) | ITGB1ITGA4POLBSMN1; SMN2ITGB3 | |
| SCHEMBL7468071 | 0.88 | ITGB1 (0.44) | ITGB1ITGA4SMN1; SMN2ITGB7MEN1 | |
| SCHEMBL7466878 | 0.87 | ATM (0.43) | ITGB1ITGA4EPHX2MAPTSMN1; SMN2 | |
| SCHEMBL7467449 | 0.87 | ATM (0.43) | ITGB1ITGA4EPHX2MAPTSMN1; SMN2 | |
| SCHEMBL7467369 | 0.86 | ITGB1 (0.51) | ITGB1ITGA4POLBSMN1; SMN2ITGB3 | |
| SCHEMBL7463859 | 0.83 | ITGB1 (0.55) | ITGB1ITGA4POLBSMN1; SMN2ITGB7 | |
| SCHEMBL7468112 | 0.80 | ITGB3 (0.50) | ITGB1ITGA4POLBMAPTSMN1; SMN2 | |
| SCHEMBL6346378 | 0.80 | POLB (0.51) | ITGB1ITGA4POLBMAPTSMN1; SMN2 | |
| SCHEMBL7468535 | 0.79 | ATM (0.45) | ITGB1ITGA4EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |