Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471264 | 0.87 | GPR119 (0.48) | GPR119KMT2ADPP4ALDH1A1SMYD3 | |
| Hydrochloric Acid SCHEMBL7471808 | 0.83 | GPR119 (0.48) | GPR119KMT2AMEN1DPP4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7468593 | 0.82 | MCHR1 (0.47) | GPR119DPP4ALDH1A1PDCD1CD274 | |
| SCHEMBL7461457 | 0.81 | GPR119 (0.50) | GPR119KMT2AMEN1DPP4ALDH1A1 | |
| SCHEMBL7473126 | 0.77 | GPR119 (0.47) | GPR119DPP4ALDH1A1HPGDHRH3 | |
| SCHEMBL7475656 | 0.77 | GPR119 (0.47) | GPR119KMT2AMEN1DPP4ALDH1A1 | |
| SCHEMBL7462540 | 0.77 | GPR119 (0.45) | GPR119KMT2AMEN1DPP4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7470297 | 0.77 | ALDH1A1 (0.45) | GPR119DPP4ALDH1A1HPGDL3MBTL3 | |
| SCHEMBL9209254 | 0.77 | HTR2B (0.42) | KMT2AMEN1ALDH1A1HRH3KCNH2 | |
| SCHEMBL7471449 | 0.76 | GPR119 (0.44) | GPR119KMT2AMEN1DPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |