Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463544 | 0.97 | STAT1 (0.43) | STAT1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7462823 | 0.92 | STAT1 (0.51) | STAT1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7460966 | 0.88 | STAT1 (0.45) | STAT1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7470639 | 0.84 | STAT1 (0.52) | STAT1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7468739 | 0.84 | PDE5A (0.46) | HTTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7469504 | 0.84 | SMN1; SMN2 (0.59) | HTTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7459198 | 0.83 | MEN1 (0.53) | HTTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7470716 | 0.83 | STAT1 (0.42) | STAT1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7463395 | 0.81 | HTT (0.55) | HTTMEN1KMT2AALDH1A1PDE5A | |
| SCHEMBL7466553 | 0.81 | STAT1 (0.52) | STAT1HTTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |