Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466553 | 0.97 | STAT1 (0.52) | STAT1MAPK1EPHA2KDREPHB4 | |
| SCHEMBL7473060 | 0.90 | STAT1 (0.64) | STAT1MAPK1HTTRAF1KDM4E | |
| SCHEMBL7467142 | 0.84 | STAT1 (0.43) | STAT1MAPK1EPHA2KDREPHB4 | |
| SCHEMBL7465501 | 0.84 | STAT1 (0.56) | STAT1MAPK1HTTRAF1KDM4E | |
| SCHEMBL7463544 | 0.81 | STAT1 (0.43) | STAT1MAPK1EPHA2KDREPHB4 | |
| SCHEMBL7470701 | 0.81 | PDE5A (0.56) | STAT1MAPK1HTTRAF1KDM4E | |
| SCHEMBL7464129 | 0.81 | MAPK1 (0.69) | STAT1MAPK1HTTKDM4EMEN1 | |
| SCHEMBL4725990 | 0.80 | MAPK1 (0.59) | STAT1MAPK1HTTRAF1KDM4E | |
| SCHEMBL7474668 | 0.80 | HTT (0.63) | MAPK1HTTKDM4EMEN1KMT2A | |
| SCHEMBL7473136 | 0.80 | STAT1 (0.52) | STAT1MAPK1HTTRAF1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |