Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GALR3 | O60755 | 2/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462823 | 0.92 | STAT1 (0.51) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL7471138 | 0.90 | MAPT (0.45) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL7467721 | 0.88 | MEN1 (0.45) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL7464149 | 0.87 | HTR6 (0.44) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL7464822 | 0.87 | ACHE (0.46) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL7460966 | 0.86 | STAT1 (0.45) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL7466302 | 0.86 | HTT (0.45) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL7472747 | 0.85 | HTT (0.49) | MAPK1KMT2AMAPTHTTRAB9A | |
| SCHEMBL7469384 | 0.85 | HTT (0.46) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL7471116 | 0.85 | HTT (0.52) | MEN1KMT2AMAPTHTTNR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |