Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687421 | 1.00 | ITGB1 (0.51) | ITGB1ITGA4POLBSMN1; SMN2ITGB3 | |
| SCHEMBL7468112 | 0.92 | ITGB3 (0.50) | ITGB1ITGA4POLBSMN1; SMN2ITGB3 | |
| SCHEMBL7472719 | 0.89 | ITGB1 (0.49) | ITGB1ITGA4POLBSMN1; SMN2ITGB3 | |
| SCHEMBL7467434 | 0.89 | ITGB1 (0.50) | ITGB1ITGA4POLBSMN1; SMN2ITGB3 | |
| SCHEMBL7467369 | 0.87 | ITGB1 (0.51) | ITGB1ITGA4POLBSMN1; SMN2ITGB3 | |
| SCHEMBL7467208 | 0.87 | ITGB1 (0.42) | ITGB1ITGA4POLB | |
| SCHEMBL7465560 | 0.87 | ITGB1 (0.42) | ITGB1ITGA4POLB | |
| SCHEMBL7463859 | 0.86 | ITGB1 (0.55) | ITGB1ITGA4POLBSMN1; SMN2ITGB7 | |
| SCHEMBL7470973 | 0.79 | ANPEP (0.46) | ITGB1ITGA4POLBSMN1; SMN2 | |
| SCHEMBL7214822 | 0.79 | ANPEP (0.46) | ITGB1ITGA4POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |