Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467255 | 1.00 | HIF1A (0.41) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL7470560 | 0.93 | HIF1A (0.38) | HIF1AMAPK14PTPN1RXFP1 | |
| SCHEMBL7470567 | 0.93 | HIF1A (0.38) | HIF1AMAPK14PTPN1RXFP1 | |
| SCHEMBL8180159 | 0.92 | HIF1A (0.40) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL8180157 | 0.92 | HIF1A (0.40) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL7465783 | 0.90 | MAOB (0.47) | HIF1A | |
| SCHEMBL7465781 | 0.90 | MAOB (0.47) | HIF1A | |
| SCHEMBL7462687 | 0.90 | MAOB (0.47) | HIF1A | |
| SCHEMBL7741768 | 0.88 | HIF1A (0.34) | HIF1A | |
| SCHEMBL7469944 | 0.87 | ALDH1A1 (0.35) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-B1 | PESTICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-6420423-B1 | PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| US-5985921-A | OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS | NOVARTIS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |