Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417874 | 0.88 | RXFP1 (0.54) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7935548 | 0.87 | KMT2A (0.55) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4733777 | 0.87 | KMT2A (0.55) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6510276 | 0.87 | KMT2A (0.68) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11775995 | 0.84 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4784357 | 0.84 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31058534 | 0.84 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7761150 | 0.83 | KDM4E (0.74) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5928755 | 0.83 | ABL1 (0.58) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1801205 | 0.82 | KDM4E (0.60) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869122-B1 | Quinolinic sulfide derivatives acting as NMDA receptor antagonists and process for preparation thereof | KOREA RES INST CHEM TECH (KR) | 2002-12-04 | — | — | EP | disclosed |
| US-5990126-A | 4-HYDROXY-QUINOLIN-2-ONE DERIVATIVES SUBSTITUTED AT POSITION 3 WITH A SUBSTITUTED AROMATIC- OR HETEROAROMATIC-SULFIDE GROUP; ANTAGONIST OF EXCITATORY AMINO ACID FOR NMDA RECEPTORS; TREATING EPILEPSY, STROKE, PARKINSON'S DISEASE | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-11-23 | — | — | US | disclosed |
| EP-0869122-A1 | Quinolinic sulfide derivatives acting as NMDA receptor antagonists and process for preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-10-07 | — | — | EP | disclosed |