Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261834 | 0.85 | L3MBTL3 (0.55) | L3MBTL3L3MBTL1OPRM1HTR2BCHRM2 | |
| SCHEMBL4957515 | 0.84 | L3MBTL3 (0.51) | L3MBTL3L3MBTL1OPRM1HTR2BCHRM2 | |
| SCHEMBL3263017 | 0.84 | L3MBTL3 (0.72) | L3MBTL3L3MBTL1OPRM1HTR2BCHRM2 | |
| SCHEMBL3069120 | 0.84 | L3MBTL3 (0.67) | L3MBTL3L3MBTL1OPRM1HTR2BCHRM2 | |
| SCHEMBL17460137 | 0.84 | SLC18A3 (0.57) | L3MBTL3L3MBTL1CYP2D6KMT2AALDH1A1 | |
| SCHEMBL6948721 | 0.83 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1OPRM1HTR2BCHRM2 | |
| SCHEMBL3311978 | 0.83 | L3MBTL3 (0.70) | L3MBTL3L3MBTL1OPRM1HTR2BCHRM2 | |
| SCHEMBL6840171 | 0.83 | L3MBTL3 (0.70) | L3MBTL3L3MBTL1OPRM1HTR2BCHRM2 | |
| SCHEMBL7468276 | 0.83 | CYP2D6 (0.44) | L3MBTL3L3MBTL1OPRM1CHRM2CYP2D6 | |
| SCHEMBL493687 | 0.81 | L3MBTL1 (0.51) | L3MBTL3L3MBTL1OPRM1HTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
| EP-0888337-B1 | PIPERIDONE TACHYKININ ANTAGONISTS | PFIZER RES & DEV (IE) | 2002-06-05 | — | — | EP | disclosed |
| US-6262075-B1 | Piperidone tachykinin antagonists | PFIZER INC | 2001-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | IL2RA, CD74, IL2 | L3MBTL3 3924/4885L3MBTL1 4111/4885OPRM1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.