Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 18/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219807 | 0.90 | ITGB1 (0.54) | NPC1RAB9AITGB1ITGA4 | |
| SCHEMBL7464092 | 0.88 | RAB9A (0.48) | NPC1RAB9AKMT2A | |
| SCHEMBL7465207 | 0.88 | RAB9A (0.48) | NPC1RAB9AKMT2A | |
| SCHEMBL7467339 | 0.87 | KMT2A (0.45) | RAB9AITGB1ITGA4KMT2A | |
| SCHEMBL7461109 | 0.87 | KMT2A (0.45) | RAB9AITGB1ITGA4KMT2A | |
| SCHEMBL7472953 | 0.86 | ITGB1 (0.51) | NPC1RAB9AITGB1ITGA4 | |
| SCHEMBL7467296 | 0.86 | RAB9A (0.50) | NPC1RAB9AKMT2A | |
| SCHEMBL7463043 | 0.86 | RAB9A (0.50) | NPC1RAB9AKMT2A | |
| SCHEMBL7461673 | 0.86 | ITGB1 (0.49) | ITGB1ITGA4 | |
| SCHEMBL7472784 | 0.85 | NPC1 (0.50) | NPC1RAB9AITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |