Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467474 | 0.88 | HRAS (0.47) | MAPTMAPK1BRD4BCHECFTR | |
| Hydrochloric Acid SCHEMBL7469233 | 0.86 | MAPT (0.50) | MAPTMAPK1MMP2MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL7471319 | 0.83 | HRAS (0.48) | MAPTMAPK1MMP2MMP9MMP8 | |
| SCHEMBL7477278 | 0.82 | MAPT (0.42) | MAPTMAPK1BRD4BCHEMLLT1 | |
| SCHEMBL5560010 | 0.82 | MAPT (0.39) | MAPTMAPK1BRD4NAMPTPOLB | |
| SCHEMBL5561204 | 0.79 | RHEB (0.41) | MAPTMAPK1BRD4MMP2MMP9 | |
| SCHEMBL14879048 | 0.75 | LCK (0.46) | MAPTMAPK1POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7471999 | 0.74 | HRAS (0.52) | MAPTMAPK1CFTR | |
| SCHEMBL7472023 | 0.73 | HRAS (0.51) | MAPTMAPK1MMP2MMP9MMP8 | |
| SCHEMBL15233045 | 0.72 | KDM4E (0.47) | MAPTMAPK1BRD4MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |