Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471355 | 0.84 | MAPT (0.43) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7473157 | 0.84 | MAPT (0.43) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7470258 | 0.83 | HPGD (0.46) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7465939 | 0.83 | MAPT (0.43) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7462715 | 0.82 | MAPT (0.42) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7467520 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2APOLBBCHE | |
| SCHEMBL5559865 | 0.80 | MEN1 (0.47) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL5333969 | 0.79 | CHEK2 (0.47) | MAPTMEN1KMT2APOLBNPC1 | |
| SCHEMBL7462181 | 0.78 | ALDH1A1 (0.51) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7460611 | 0.77 | CNR1 (0.39) | MAPTMEN1KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |