Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.34 |
| ▸ | PYGL | P06737 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PLD2 | O14939 | 1/20 | 0.31 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461505 | 0.94 | P4HB (0.41) | P4HBHSP90AA1ABCB1PYGLKDM4E | |
| SCHEMBL7462825 | 0.94 | KMT2A (0.41) | P4HBHSP90AA1ABCB1PYGLKDM4E | |
| SCHEMBL7467832 | 0.91 | P4HB (0.47) | P4HBHSP90AA1KDM4ERAB9AALDH1A1 | |
| SCHEMBL8831163 | 0.90 | P4HB (0.34) | P4HBHSP90AA1ABCB1KDM4ENPC1 | |
| SCHEMBL7458517 | 0.90 | P4HB (0.34) | P4HBHSP90AA1ABCB1KDM4ENPC1 | |
| SCHEMBL7468222 | 0.90 | NPC1 (0.37) | ABCB1PYGLKDM4ENPC1RAB9A | |
| SCHEMBL7470059 | 0.89 | P4HB (0.37) | P4HBHSP90AA1ABCB1 | |
| SCHEMBL8831002 | 0.89 | ABCB1 (0.33) | P4HBHSP90AA1ABCB1KDM4ENPC1 | |
| SCHEMBL7462648 | 0.88 | KMT2A (0.41) | P4HBHSP90AA1ABCB1PYGLKDM4E | |
| SCHEMBL7473569 | 0.86 | P4HB (0.34) | P4HBHSP90AA1ABCB1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |