Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | F11 | P03951 | 3/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627433 | 0.92 | MAPT (0.38) | ABCB1KDM4EMAPT | |
| SCHEMBL7461465 | 0.90 | ABCB1 (0.33) | P4HBHSP90AA1ABCB1 | |
| SCHEMBL7475427 | 0.88 | KMT2A (0.33) | ABCB1KDM4EMAPTF11 | |
| SCHEMBL7465517 | 0.88 | KDM4E (0.36) | KDM4EMAPT | |
| SCHEMBL7464956 | 0.88 | KDM4E (0.35) | KDM4EMAPT | |
| SCHEMBL7468851 | 0.88 | MAPT (0.38) | ABCB1KDM4EMAPT | |
| SCHEMBL7473629 | 0.87 | P4HB (0.34) | P4HBHSP90AA1ABCB1KDM4EF11 | |
| SCHEMBL7474788 | 0.87 | P4HB (0.34) | P4HBHSP90AA1 | |
| SCHEMBL7467645 | 0.86 | P4HB (0.41) | P4HBHSP90AA1ABCB1KDM4EMAPT | |
| SCHEMBL7462825 | 0.84 | KMT2A (0.41) | P4HBHSP90AA1ABCB1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |