Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | LIPE | Q05469 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 5/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656865 | 0.89 | FFAR1 (0.49) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL6747740 | 0.88 | APP (0.50) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL6831004 | 0.84 | TSHR (0.50) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL31556121 | 0.84 | APP (0.54) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL2799748 | 0.84 | ABCB1 (0.57) | MAPTMAPK1TDP1L3MBTL1APP | |
| SCHEMBL23258900 | 0.84 | L3MBTL1 (0.52) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL6752182 | 0.84 | AGXT (0.54) | MAPTMAPK1TDP1L3MBTL1FFAR1 | |
| SCHEMBL339812 | 0.84 | MAPT (0.71) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL34467005 | 0.83 | TDP1 (0.55) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL23883826 | 0.83 | TDP1 (0.55) | MAPTMAPK1TDP1L3MBTL1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530241-B | Preparation method of benzo ring derivative with benzyl quaternary carbon center | 武汉大学 | 2021-02-02 | — | — | CN | claimed |
| WO-2025132542-A1 | MACROCYCLIC OREXIN AGONISTS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-26 | — | — | WO | disclosed |
| CN-115286605-B | Method for synthesizing isochromanone compounds based on carbon monoxide gas or carbon monoxide alternative source | 武汉大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-114478211-B | Preparation method of etazocine intermediate | 广州一品红制药有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-114478213-B | Method for preparing etazocine intermediate by utilizing micro-channel device | 广州一品红制药有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-113372184-B | Method for synthesizing C-N axis chiral phenanthridinone compound based on chiral transfer strategy | 武汉大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-115594582-A | Synthesis of 13 Method and application of C-marked 4-trifluoromethyl aryl formate | 武汉大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115286605-A | Method for synthesizing isochromanone compounds based on carbon monoxide gas or carbon monoxide substitute source | 武汉大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-114478211-A | Preparation method of eptazocine intermediate | 广州一品红制药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478213-A | Method for preparing eptazocine intermediate by using microchannel device | 广州一品红制药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| US-6528529-B1 | 4-Methoxy-1-(4-(2-methylphenyl)-4-oxo-1-butyl)piperidine | ACADIA PHARMACEUTICALS INC. | 2003-03-04 | — | — | US | disclosed |
| WO-2003002157-A1 | SOLID-PHASE NUCLEOPHILIC FLUORINATION | AMERSHAM PLC (GB) | 2003-01-09 | — | — | WO | disclosed |
| CN-1303376-A | Compound with activity on muscarinic receptors | ACADIA PHARMACEUTICAL INC (US) | 2001-07-11 | — | — | CN | disclosed |
| WO-2001005763-A2 | COMPOUNDS WITH ACTIVITY ON MUSCARINIC RECEPTORS | ACADIA PHARMACEUTICALS, INC. (US) | 2001-01-25 | — | — | WO | disclosed |
| EP-1068185-A1 | COMPOUNDS WITH ACTIVITY ON MUSCARINIC RECEPTORS | Acadia Pharmaceuticals Inc. (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0733033-B1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LTD (GB) | 1999-12-22 | — | — | EP | disclosed |
| WO-1999050247-A1 | COMPOUNDS WITH ACTIVITY ON MUSCARINIC RECEPTORS | ACADIA PHARMACEUTICALS, INC. (US) | 1999-10-07 | — | — | WO | disclosed |
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| EP-0485026-A2 | Antimanic phenoxymethylene bisphosphonate derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-05-13 | — | — | EP | disclosed |