Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463491 | 0.91 | STS (0.34) | MAPTLMNATHRBALDH1A1KMT2A | |
| SCHEMBL7468266 | 0.86 | KDM4E (0.40) | MAPTLMNAALDH1A1POLBKMT2A | |
| SCHEMBL7463597 | 0.85 | MAPT (0.44) | MAPTLMNATHRBALDH1A1TP53 | |
| SCHEMBL7470407 | 0.83 | MAPT (0.45) | MAPTLMNATHRBALDH1A1TP53 | |
| SCHEMBL7467133 | 0.83 | PTPN1 (0.31) | — | |
| SCHEMBL8556270 | 0.83 | MAPT (0.37) | MAPTLMNATHRBALDH1A1TP53 | |
| SCHEMBL7475408 | 0.82 | MAPK8 (0.40) | MAPTLMNATHRBALDH1A1TP53 | |
| SCHEMBL7029465 | 0.82 | MAPT (0.40) | MAPTLMNATHRBTP53POLB | |
| SCHEMBL7466240 | 0.80 | MAPT (0.39) | MAPTLMNATHRBALDH1A1TP53 | |
| SCHEMBL7469012 | 0.79 | MAPT (0.41) | MAPTLMNATHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859774-B1 | SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |