Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483727 | 0.75 | — | — | |
| SCHEMBL15240100 | 0.72 | ALOX15 (0.33) | LMNAALOX15 | |
| SCHEMBL19396334 | 0.70 | — | — | |
| SCHEMBL27655474 | 0.70 | ALOX15 (0.39) | LMNAHSD17B10ALOX15 | |
| SCHEMBL27716387 | 0.70 | LMNA (0.35) | LMNAALOX15 | |
| SCHEMBL6113452 | 0.69 | — | — | |
| SCHEMBL14790645 | 0.67 | USP2 (0.35) | — | |
| SCHEMBL21295188 | 0.67 | LMNA (0.42) | LMNA | |
| SCHEMBL2906410 | 0.65 | — | — | |
| SCHEMBL15352693 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946502-A1 | SULFONAMIDE INTERLEUKIN-BETA CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998016505-A1 | SULFONAMIDE INTERLEUKIN-1β CONVERTING ENZYME INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |