Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469565 | 0.90 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL10203304 | 0.85 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL893796 | 0.85 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNAPOLBMEN1 | |
| SCHEMBL4366597 | 0.84 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNAPKMPOLB | |
| SCHEMBL5173012 | 0.84 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNAPKMPOLB | |
| SCHEMBL6508896 | 0.84 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNAPKMPOLB | |
| SCHEMBL7411698 | 0.83 | NPC1 (0.61) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL8295418 | 0.82 | HDAC8 (0.55) | ALDH1A1SMN1; SMN2LMNAGLAPKM | |
| SCHEMBL6470048 | 0.82 | HDAC8 (0.55) | ALDH1A1SMN1; SMN2LMNAGLAPKM | |
| SCHEMBL18094981 | 0.82 | POLB (0.49) | ALDH1A1SMN1; SMN2LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |