Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206463 | 0.87 | HRH3 (0.55) | CYP4A11ALDH1A1HTTCYP4F2LOXL2 | |
| SCHEMBL7471752 | 0.87 | SMN1; SMN2 (0.56) | CYP4A11ALDH1A1CYP4F2LOXL2KDM4E | |
| SCHEMBL4741255 | 0.85 | LOXL2 (0.53) | CYP4A11ALDH1A1CYP4F2LOXL2KDM4E | |
| SCHEMBL5776546 | 0.85 | CYP4A11 (0.57) | CYP4A11ALDH1A1CYP4F2LMNALOXL2 | |
| SCHEMBL5068516 | 0.83 | HDAC8 (0.65) | CYP4A11ALDH1A1CYP4F2LOXL2ACHE | |
| SCHEMBL24885671 | 0.83 | ACHE (0.45) | CYP4A11ALDH1A1HTTCYP4F2LMNA | |
| SCHEMBL10995347 | 0.81 | LPAR1 (0.50) | CYP4A11ALDH1A1CYP4F2LOXL2KDM4E | |
| SCHEMBL24835284 | 0.81 | CYP4A11 (0.60) | CYP4A11ALDH1A1HTTCYP4F2LMNA | |
| Methylparaben SCHEMBL9443679 | 0.81 | CA1 (0.69) | CYP4A11ALDH1A1CYP4F2LMNALOXL2 | |
| SCHEMBL15392053 | 0.81 | MAPT (0.61) | CYP4A11ALDH1A1LOXL2ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |