Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.35 |
| ▸ | DRD3 | P35462 | 13/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468477 | 1.00 | DRD2 (0.35) | DRD2DRD3MCHR1F2F10 | |
| SCHEMBL7474107 | 0.91 | PARP1 (0.38) | DRD2DRD3F2F10HRH3 | |
| SCHEMBL7474111 | 0.91 | PARP1 (0.38) | DRD2DRD3F2F10HRH3 | |
| SCHEMBL8562707 | 0.90 | F2 (0.35) | DRD2DRD3F2F10HTR4 | |
| SCHEMBL8562703 | 0.90 | F2 (0.35) | DRD2DRD3F2F10HTR4 | |
| SCHEMBL8564964 | 0.90 | F2 (0.35) | DRD2DRD3F2F10ACHE | |
| SCHEMBL8564972 | 0.90 | F2 (0.35) | DRD2DRD3F2F10ACHE | |
| Hydrochloric Acid SCHEMBL8561453 | 0.89 | F2 (0.35) | DRD2DRD3F2F10HRH3 | |
| SCHEMBL7475227 | 0.89 | DRD2 (0.36) | DRD2DRD3F2F10 | |
| SCHEMBL7475221 | 0.89 | DRD2 (0.36) | DRD2DRD3F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |