Urea

Urea

SCHEMBL7468626

CC=CCCCN.NC(N)=O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.42
FAAH O00519 3/20 0.42
KMT2A Q03164 3/20 0.42
SOAT1 P35610 2/20 0.42
MEN1 O00255 2/20 0.42
CYP2C19 P33261 2/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
CNR1 P21554 2/20 0.39
PAOX Q6QHF9 1/20 0.39
SLC6A5 Q9Y345 3/20 0.39
THRB P10828 3/20 0.39
LMNA P02545 3/20 0.39
BLM P54132 3/20 0.39
NPSR1 Q6W5P4 3/20 0.39
GABRR3 A8MPY1 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
HDAC3 O15379 1/20 0.39
GABBR2 O75899 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134345 0.87
SCHEMBL466588 0.87
SCHEMBL11743056 0.87
Urea SCHEMBL7466232 0.85 FAAH (0.35) CYP1A2FAAHKMT2ASOAT1MEN1
SCHEMBL13626153 0.80
SCHEMBL1270704 0.80
SCHEMBL1270703 0.80
SCHEMBL466709 0.79
SCHEMBL16056 0.79
SCHEMBL11740831 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3194538-A1 DISPERSANT VISCOSITY MODIFIERS WITH AMINE FUNCTIONALITY The Lubrizol Corporation (US) 2017-07-26 EP claimed
WO-2016044254-A1 DISPERSANT VISCOSITY MODIFIERS WITH AMINE FUNCTIONALITY THE LUBRIZOL CORPORATION (US) 2016-03-24 WO claimed
EP-0810996-B1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS HE ZHIQIANG ALEX (US) 2002-10-09 EP claimed
EP-0810996-A1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS He, Zhiqiang Alex (US) 1997-12-10 EP claimed
WO-1996026189-A1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS HE ZHIGIANG ALEX (US) 1996-08-29 WO claimed
EP-3194538-B1 USE OF DISPERSANT VISCOSITY MODIFIERS WITH AMINE FUNCTIONALITY LUBRIZOL CORP (US) 2023-07-12 EP disclosed
US-20190112542-A1 DISPERSANT VISCOSITY MODIFIERS WITH AMINE FUNCTIONALITY THE LUBRIZOL CORPORATION (US) 2019-04-18 US disclosed
US-20170275556-A1 DISPERSANT VISCOSITY MODIFIERS WITH AMINE FUNCTIONALITY THE LUBRIZOL CORPORATION 2017-09-28 US disclosed
EP-3194538-A1 DISPERSANT VISCOSITY MODIFIERS WITH AMINE FUNCTIONALITY The Lubrizol Corporation (US) 2017-07-26 EP disclosed
WO-2016044254-A1 DISPERSANT VISCOSITY MODIFIERS WITH AMINE FUNCTIONALITY THE LUBRIZOL CORPORATION (US) 2016-03-24 WO disclosed
EP-0810996-B1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS HE ZHIQIANG ALEX (US) 2002-10-09 EP disclosed
US-5746946-A Imidazolidinone derivatives as corrosion inhibitors KING IDUSTRIES, INC. (US) 1998-05-05 US disclosed
EP-0810996-A1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS He, Zhiqiang Alex (US) 1997-12-10 EP disclosed
WO-1996026189-A1 IMIDAZOLIDINONE DERIVATIVES AS CORROSION INHIBITORS HE ZHIGIANG ALEX (US) 1996-08-29 WO disclosed