Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 8/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557746 | 0.92 | TSHR (0.45) | TSHRMAOBALDH1A1SMN1; SMN2XIAP | |
| SCHEMBL7473022 | 0.92 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL8551630 | 0.88 | TSHR (0.43) | TSHRMAOBALDH1A1SMN1; SMN2XIAP | |
| SCHEMBL8554111 | 0.87 | TSHR (0.48) | TSHRALDH1A1SMN1; SMN2XIAPPPARG | |
| SCHEMBL8605061 | 0.87 | TSHR (0.53) | TSHRALDH1A1SMN1; SMN2XIAPPPARG | |
| SCHEMBL8551698 | 0.86 | ALDH1A1 (0.45) | TSHRMAOBALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL7468721 | 0.85 | ALDH1A1 (0.44) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8603405 | 0.85 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2XIAPMEN1 | |
| SCHEMBL8553538 | 0.85 | TSHR (0.49) | TSHRPPARG | |
| SCHEMBL8602742 | 0.85 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2XIAPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | claimed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |