Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 10/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473022 | 0.94 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TSHRPPARG | |
| SCHEMBL8555694 | 0.92 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TSHRMAOBGSK3B | |
| SCHEMBL8595934 | 0.91 | TSHR (0.44) | ALDH1A1SMN1; SMN2TSHRGSK3BADK | |
| SCHEMBL8602443 | 0.89 | HTT (0.51) | ALDH1A1TSHRMAOBPPARG | |
| SCHEMBL8554310 | 0.89 | TSHR (0.48) | ALDH1A1SMN1; SMN2TSHRPPARG | |
| SCHEMBL7468643 | 0.86 | TSHR (0.42) | ALDH1A1SMN1; SMN2TSHRMAOBGSK3B | |
| SCHEMBL7468721 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TSHRGSK3BADK | |
| SCHEMBL8557746 | 0.84 | TSHR (0.45) | ALDH1A1SMN1; SMN2TSHRMAOBGSK3B | |
| SCHEMBL8594197 | 0.84 | TSHR (0.45) | ALDH1A1SMN1; SMN2TSHRGSK3BADK | |
| SCHEMBL8554130 | 0.84 | TSHR (0.43) | ALDH1A1SMN1; SMN2TSHRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |