Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467252 | 0.87 | PSEN1 (0.41) | ALDH1A1KDM4EL3MBTL1NOD2NOD1 | |
| SCHEMBL10487940 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4EL3MBTL1RAB9AMEN1 | |
| SCHEMBL9049818 | 0.78 | KMT2A (0.59) | ALDH1A1KDM4EL3MBTL1RAB9AMEN1 | |
| SCHEMBL7467388 | 0.76 | PSEN1 (0.42) | ALDH1A1KDM4ENOD2NOD1HPGD | |
| SCHEMBL7460536 | 0.76 | MAPT (0.52) | ALDH1A1MEN1KMT2ACA12CA1 | |
| SCHEMBL7470720 | 0.75 | PSEN1 (0.43) | ALDH1A1KDM4EHPGDTSHRPSEN1 | |
| SCHEMBL10487864 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4EL3MBTL1RAB9AMEN1 | |
| SCHEMBL10487900 | 0.74 | MEN1 (0.72) | ALDH1A1KDM4EL3MBTL1RAB9AMEN1 | |
| SCHEMBL10487922 | 0.74 | LMNA (0.61) | ALDH1A1KDM4EL3MBTL1RAB9AMEN1 | |
| SCHEMBL10487974 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |