Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 17/20 | 0.81 |
| ▸ | ACHE | P22303 | 17/20 | 0.81 |
| ▸ | MAOA | P21397 | 5/20 | 0.72 |
| ▸ | MAOB | P27338 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | NAMPT | P43490 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468962 | 1.00 | BCHE (0.81) | BCHEACHEMAOAMAOBCYP3A4 | |
| Hydrochloric Acid SCHEMBL4009736 | 0.99 | BCHE (0.79) | BCHEACHEMAOAMAOBCYP3A4 | |
| Hydrochloric Acid SCHEMBL4231207 | 0.99 | BCHE (0.79) | BCHEACHEMAOAMAOBCYP3A4 | |
| SCHEMBL83014 | 0.93 | NAMPT (0.74) | BCHEACHEMAOAMAOBCYP3A4 | |
| SCHEMBL83013 | 0.93 | NAMPT (0.74) | BCHEACHEMAOAMAOBCYP3A4 | |
| SCHEMBL9650895 | 0.90 | ACHE (1.00) | BCHEACHEMAOAMAOB | |
| SCHEMBL9650908 | 0.90 | ACHE (1.00) | BCHEACHEMAOAMAOB | |
| Hydrochloric Acid SCHEMBL9374592 | 0.89 | BCHE (0.98) | BCHEACHEMAOAMAOB | |
| Hydrochloric Acid SCHEMBL9374603 | 0.89 | BCHE (0.98) | BCHEACHEMAOAMAOB | |
| SCHEMBL83173 | 0.88 | NAMPT (0.70) | BCHEACHEMAOAMAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923570-B1 | PYRIDYL ALKENE- AND PYRIDYL ALKINE- ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | FUJISAWA DEUTSCHLAND GMBH (DE) | 2002-09-25 | — | — | EP | claimed |
| EP-0330026-B1 | Piperidinoalkyl derivatives of carboxylic acid amides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-10-05 | — | — | EP | claimed |
| US-5169856-A | Cholinesterase antagonists | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 1992-12-08 | — | — | US | claimed |
| EP-0330026-A1 | Piperidinoalkyl derivatives of carboxylic acid amides | Takeda Chemical Industries, Ltd. (JP) | 1989-08-30 | — | — | EP | claimed |