Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 19/20 | 1.00 |
| ▸ | BCHE | P06276 | 18/20 | 1.00 |
| ▸ | MAOA | P21397 | 5/20 | 0.88 |
| ▸ | MAOB | P27338 | 4/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650908 | 1.00 | ACHE (1.00) | ACHEBCHEMAOAMAOBHDAC3 | |
| Hydrochloric Acid SCHEMBL9374603 | 0.99 | BCHE (0.98) | ACHEBCHEMAOAMAOBHDAC3 | |
| Hydrochloric Acid SCHEMBL9374592 | 0.99 | BCHE (0.98) | ACHEBCHEMAOAMAOBHDAC3 | |
| SCHEMBL7468965 | 0.90 | BCHE (0.81) | ACHEBCHEMAOAMAOB | |
| SCHEMBL7468962 | 0.90 | BCHE (0.81) | ACHEBCHEMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4009736 | 0.89 | BCHE (0.79) | ACHEBCHEMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4231207 | 0.89 | BCHE (0.79) | ACHEBCHEMAOAMAOB | |
| SCHEMBL9374448 | 0.86 | BCHE (0.75) | ACHEBCHEMAOAMAOB | |
| SCHEMBL9374436 | 0.86 | BCHE (0.75) | ACHEBCHEMAOAMAOB | |
| Hydrochloric Acid SCHEMBL5524879 | 0.85 | BCHE (0.74) | ACHEBCHEMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169856-A | Cholinesterase antagonists | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 1992-12-08 | — | — | US | claimed |
| US-5169856-A | Cholinesterase antagonists | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 1992-12-08 | — | — | US | disclosed |