Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 10/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462263 | 0.84 | PDGFRB (0.64) | PDGFRBACHEBACE1LMNACYP1A2 | |
| SCHEMBL7473621 | 0.80 | PDGFRB (0.60) | PDGFRBACHEBACE1LMNAALDH1A1 | |
| SCHEMBL7473557 | 0.79 | PDGFRB (0.59) | PDGFRBACHEBACE1LMNAUSP2 | |
| SCHEMBL7973030 | 0.79 | PDGFRB (0.66) | PDGFRBACHEBACE1KITPDGFRA | |
| SCHEMBL7468972 | 0.78 | PDGFRB (0.68) | PDGFRBACHEBACE1ALDH1A1KIT | |
| SCHEMBL7469281 | 0.76 | PDGFRB (0.51) | PDGFRBACHEBACE1LMNAUSP2 | |
| SCHEMBL2922036 | 0.73 | PDGFRB (0.59) | PDGFRBACHEBACE1LMNAALDH1A1 | |
| SCHEMBL2922917 | 0.73 | PDGFRB (0.73) | PDGFRBKITPDGFRA | |
| SCHEMBL2915899 | 0.72 | PDGFRB (1.00) | PDGFRBKITPDGFRAFLT3 | |
| SCHEMBL30275314 | 0.70 | EGFR (0.54) | PDGFRBLMNACYP3A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |