Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.57 |
| ▸ | MMP13 | P45452 | 11/20 | 0.57 |
| ▸ | MMP2 | P08253 | 11/20 | 0.57 |
| ▸ | MMP14 | P50281 | 8/20 | 0.57 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.57 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.57 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.57 |
| ▸ | MMP9 | P14780 | 7/20 | 0.43 |
| ▸ | MMP8 | P22894 | 5/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.43 |
| ▸ | MMP16 | P51512 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299253 | 0.85 | MMP1 (0.76) | MMP1MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL7298937 | 0.75 | MMP1 (0.61) | MMP1MMP13MMP2MMP14MMP9 | |
| SCHEMBL7301493 | 0.75 | MMP1 (0.76) | MMP1MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL7309090 | 0.74 | MMP1 (0.80) | MMP1MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL7301387 | 0.74 | MMP1 (0.79) | MMP1MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL7462489 | 0.72 | MMP1 (0.55) | MMP1MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL7308211 | 0.72 | MMP1 (0.76) | MMP1MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL7307897 | 0.72 | MMP1 (1.00) | MMP1MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL7303077 | 0.70 | MMP1 (0.72) | MMP1MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL5919502 | 0.70 | MMP13 (0.80) | MMP1MMP13MMP2MMP14MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171422-A1 | MMP INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063165-A1 | MMP INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-26 | — | — | WO | disclosed |