SCHEMBL746905

SCHEMBL746905

OC1(F)C=CC(c2ccccc2)=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1577845 0.81 ALDH1A1 (0.31)
Benzene SCHEMBL27857134 0.81 ALDH1A1 (0.31)
SCHEMBL222999 0.81 ALDH1A1 (0.31)
SCHEMBL30697824 0.79
Biphenyl SCHEMBL27559195 0.79 ALDH1A1 (0.35)
SCHEMBL4794114 0.79
SCHEMBL6496501 0.79 MAOB (0.33)
SCHEMBL23581152 0.78 MMP3 (0.35)
SCHEMBL5390125 0.78 MEN1 (0.30)
SCHEMBL7422830 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1034939-A None JP disclosed
CN-112117384-B Organic electroluminescent material and application thereof 北京鼎材科技有限公司 2024-01-23 CN disclosed
CN-110194743-B Phenyl (3-methoxy-4- (4-methyl-1H-imidazole-1-yl) phenyl) ketone compound 云南大学 2022-11-11 CN disclosed
CN-109503686-B Novel nucleoside phosphoramidate compounds and uses thereof 南京圣和药业股份有限公司 2022-03-11 CN disclosed
CN-114007696-A Compounds for treating oncovirus-induced cancer and methods of use thereof 塞莱斯蒂亚生物技术股份公司 2022-02-01 CN disclosed
CN-113966324-A NOTCH signaling pathway inhibitors and their use in cancer treatment 塞莱斯蒂亚生物技术股份公司 2022-01-21 CN disclosed
CN-108314697-B Novel nucleoside phosphoramidate compounds and uses thereof 南京圣和药业股份有限公司 2021-05-07 CN disclosed
CN-108546277-B Novel nucleoside phosphoramidate compounds and uses thereof 南京圣和药业股份有限公司 2021-05-07 CN disclosed
EP-2430012-A1 7-AZA-SPIRO[3.5]NONANE-7-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-03-21 EP disclosed
WO-2011089550-A1 ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI AVENTIS (FR) 2011-07-28 WO disclosed
WO-2010130945-A1 7-AZA-SPIRO[3.5]NONANE-7-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2010-11-18 WO disclosed
CN-100491323-C Biaryloxymethylarenecarboxylic acids compound HOFFMANN LA ROCHE (CH) 2009-05-27 CN disclosed
CN-1867546-A Novel compound and its uses in medicine, its preparation method and its pharmaceutical composition comprising same REDDY RES FOUNDATION (IN) 2006-11-22 CN disclosed
CN-1812956-A Biaryloxymethylarenecarboxylic acids as glycogen synthase activator HOFFMANN LA ROCHE (CH) 2006-08-02 CN disclosed
JP-S6434939-A UNSATURATED ALKOXYFLUOROBIPHENYL CHISSO CORP 1989-02-06 JP disclosed