Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGAV | P06756 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168844 | 0.94 | ITGAV (0.45) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7479025 | 0.88 | ITGB3 (0.39) | ITGB3ITGAVMAPTSMN1; SMN2MEN1 | |
| SCHEMBL13191087 | 0.87 | ITGB3 (0.47) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7479810 | 0.85 | MAPT (0.44) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7478478 | 0.84 | PTPN1 (0.41) | ITGB3ITGAVMAPTNPC1RAB9A | |
| SCHEMBL8324174 | 0.82 | ITGB3 (0.44) | ITGB3ITGAVMAPTNPC1RAB9A | |
| SCHEMBL7160779 | 0.81 | ITGB3 (0.45) | ITGB3ITGAVMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7474158 | 0.80 | ITGB3 (0.48) | ITGB3ITGAVNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7368163 | 0.80 | BACE1 (0.39) | ITGB3ITGAVMAPTHTTL3MBTL1 | |
| SCHEMBL7364374 | 0.80 | ITGB3 (0.44) | ITGB3ITGAVMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964856-B1 | BICYCLIC AMINO ACIDS | MERCK PATENT GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |